Synthetic Organic Chemistry(Uchida Lab.)
Organic synthetic reactions are quite important and fundamental technologies for the supplying various materials. However, most of organic transformations are consumed a lot of materials and energies with co-producing undesired waste materials. Development of highly selective, atom-economic and environment-friend new methodologies have been strongly required.
For the purpose of these viewpoints, we have intrigued to oxidative catalytic functionalization using high atom-economic oxidant, and achieved that highly enantioselective water-mediated epoxidation using air as an oxidant, and asymmetric nitrene transfer reaction using azide compound as a nitrene source.